God's guidance is needed because people are naturally ignorant and rebellious and there are many who lead others astray.
The need to know and do the will of God
See also
pp Mk 3:35
pp Lk 8:21
The concern of Jesus Christ to do the will of God
By themselves people are ignorant of the right way in life
blindness the result of disobedience
Warnings against false guidance
False prophets and teachers
pp Mt 23:13
False shepherds and guides
Idols and mediums
Other agencies
Despite knowing God's will, sinners still rebel against him
The adverse consequences of false guidance and disobedience