Acts 22:10
And I said, What shall I do, Lord? And the Lord said unto me, Arise, and go into Damascus; and there it shall be told thee of all things which are appointed for thee to do.
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22:1-11 The apostle addressed the enraged multitude, in the customary style of respect and good-will. Paul relates the history of his early life very particularly; he notices that his conversion was wholly the act of God. Condemned sinners are struck blind by the power of darkness, and it is a lasting blindness, like that of the unbelieving Jews. Convinced sinners are struck blind as Paul was, not by darkness, but by light. They are for a time brought to be at a loss within themselves, but it is in order to their being enlightened. A simple relation of the Lord's dealings with us, in bringing us, from opposing, to profess and promote his gospel, when delivered in a right spirit and manner, will sometimes make more impression that laboured speeches, even though it amounts not to the full proof of the truth, such as was shown in the change wrought in the apostle.See the notes on Acts 9:3-7.

Acts 22:6

As I made my journey - As I was on my journey.

About noon - Acts 26:13, "at mid-day." This circumstance is omitted by Luke in his account in Acts 9:Paul mentions it as being the more remarkable since it occurred at mid-day, to show that he was not deluded by any meteoric or natural appearances, which usually occur at night.

Acts 22:11

The glory of that light - The splendor, the intense brilliancy of the light. See this and its effects explained in the notes on Acts 9:8.

9-11. they that were with me—(See on [2096]Ac 9:7, &c.) See Poole on "Acts 9:6". Such things as Ananias told him from Christ, were as if Christ himself had told him them; and by Ananias our Saviour satisfied St. Paul’s question,

What shall I do, Lord?

And I said, what shall I do, Lord?.... See Gill on Acts 9:6. And I said, What shall I do, LORD? And the Lord said unto me, Arise, and go into Damascus; and there it shall be told thee of all things which are appointed for thee to do.
10. which are appointed for thee to do] God explained this to Ananias (see Acts 9:15), how Saul was a chosen vessel to bear His name before Gentiles and kings and the children of Israel; and still more about his labours was to be revealed to the new Apostle himself. According to Acts 26:16-18 the character of the work to which he was called was from the first indicated to Saul; though as no mention is made of Ananias in that passage, it may well be that the Apostle there brings into one statement both the words he heard on the way, and those which were afterwards spoken to him by Ananias.

Acts 22:10. Τέτακταί σοι, it is appointed for thee) The Divine appointment is the sphere of the godly: whatever they do is a realisation (repræsentatio, a vivid exhibition or ready performance) of that appointment.

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