2179. Ephesinos
Lexical Summary
Ephesinos: Ephesian

Original Word: Ἐφεσῖνος
Part of Speech: Adjective
Transliteration: Ephesinos
Pronunciation: ef-es-ee-nos
Phonetic Spelling: (ef-es-ee'-nos)
KJV: of Ephesus
Word Origin: [from G2181 (Ἔφεσος - Ephesus)]

1. Ephesine, or situated at Ephesus

Strong's Exhaustive Concordance
of Ephesus.

From Ephesos; Ephesine, or situated at Ephesus -- of Ephesus.

see GREEK Ephesos

NAS Exhaustive Concordance
Word Origin
variant reading for Ephesos, q.v.

Thayer's Greek Lexicon
STRONGS NT 2179: Ἐφεσινος

Ἐφεσινος, Ἐφεσινη, Ἐφεσινον, Ephesian: Revelation 2:1 Rec.

Topical Lexicon
Meaning and Scope

Ἐφεσῖνος denotes an inhabitant of, or something pertaining to, the city of Ephesus. While this exact adjective is not found in the Greek New Testament, the concept of “Ephesians” is central to several New Testament narratives and epistles through the closely related Ἐφέσιος (Acts 19:28; Acts 21:29). Therefore, discussion of Ἐφεσῖνος naturally overlaps with every biblical reference to the people, church, or culture of Ephesus.

Ephesus in the New Testament Era

Ephesus was the leading city of Roman Asia, situated at the mouth of the Cayster River and famed for its harbor, the temple of Artemis, and a vigorous commercial life that drew pilgrims, sailors, magicians, and merchants. This strategic location made it a natural hub for gospel expansion. The city housed a sizable Jewish population (Acts 19:8) and a thriving Gentile culture steeped in idolatry and the occult (Acts 19:18-19).

Apostolic Ministry at Ephesus

• Paul’s extended stay (Acts 19:1-20; Acts 20:31) resulted in a flourishing church and the spread of the gospel “so that all who lived in the province of Asia, both Jews and Greeks, heard the word of the Lord” (Acts 19:10).
• Signs and wonders accompanied Paul’s preaching (Acts 19:11-12). Repentance was dramatic, with practitioners of magic burning their scrolls (Acts 19:19).
• Hostility arose when the gospel threatened the idol-making trade (Acts 19:23-41). Demetrius’ riot revealed both the economic and spiritual strongholds Christ confronted.
• Paul’s farewell to the Ephesian elders (Acts 20:17-38) is a model of pastoral exhortation: “Be on guard for yourselves and for all the flock” (Acts 20:28). His tears, warnings, and prayers show the depth of apostolic affection.
• Timothy was later stationed in Ephesus to curb false teaching (1 Timothy 1:3-7).

Representative Biblical Passages

Acts 21:29 mentions “Trophimus the Ephesian,” a Gentile believer whose mere presence in Jerusalem stirred accusations against Paul.

Ephesians 1:1 underscores the spiritual identity of Ephesian believers: “To the saints in Ephesus, the faithful in Christ Jesus.”

Revelation 2:1-7 records Christ’s evaluation of the Ephesian church, commending labor and discernment yet reproving the loss of first love: “Remember then how far you have fallen” (Revelation 2:5).

Doctrinal Importance

1. Union with Christ: The Epistle to the Ephesians unfolds believers’ position “in the heavenly realms in Christ Jesus” (Ephesians 2:6).
2. Jew-Gentile Reconciliation: Through Christ, God “has destroyed the barrier… to create in Himself one new man” (Ephesians 2:14-15).
3. Spiritual Warfare: Ephesians 6:10-18 calls the church to “put on the full armor of God,” an exhortation grounded in the cosmic conflict evident in Acts 19.
4. Ecclesiology: The letter presents the church as Christ’s body and bride (Ephesians 1:22-23; 5:25-27).

Prophetic Word and Continuing Challenge

Revelation 2 shows that even a doctrinally sound church can wane in devotion. The summons to repent and do the works done at first remains relevant to every generation.

Later Church History

Early tradition associates the Apostle John with Ephesus, where he shepherded the churches of Asia and possibly compiled his Gospel. By the second century, the city hosted significant Christian leaders and, in the fifth century, the Council of Ephesus (A.D. 431) affirmed the full deity and humanity of Christ.

Practical Applications for Today

• Guard the heart: Orthodoxy must never eclipse love for Christ.
• Engage culture courageously: Gospel proclamation challenges entrenched idols—economic, philosophical, or spiritual.
• Train leaders: Paul’s mentoring of Timothy and the Ephesian elders models intentional discipleship.
• Persevere in warfare: Believers still “struggle not against flesh and blood” (Ephesians 6:12).

See Also

Ephesios (Strong’s 2180); Ephesus; Trophimus; Artemis; Timothy; Paul’s Third Missionary Journey

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