With desire I have desired - A Hebraism for, I have desired most earnestly. Our Lord's meaning seems to be, that, having purposed to redeem a lost world by his blood, he ardently longed for the time in which he was to offer himself up. Such love did the holy Jesus bear to the human race. This eucharistic passover was celebrated once, by way of anticipation, before the bloody sacrifice of the victim of salvation, and before the deliverance it was appointed to commemorate; as the figurative passover had been likewise once celebrated before the going out of Egypt, and the deliverance of God's chosen people. Quesnel.

With desire I have desired. or, I have heartily desired.

Luke 12:50 But I have a baptism to be baptized with; and how am I straitened till it be accomplished!

John 4:34 Jesus said to them, My meat is to do the will of him that sent me, and to finish his work.

John 13:1 Now before the feast of the passover, when Jesus knew that his hour was come that he should depart out of this world to the Father...

John 17:1 These words spoke Jesus, and lifted up his eyes to heaven, and said, Father, the hour is come; glorify your Son...

The Cross the victory and Defeat of Darkness
'This is your hour, and the power of darkness.' --Luke xxii. 53. The darkness was the right time for so dark a deed. The surface meaning of these pathetic and far-reaching words of our Lord's in the garden to His captors is to point the correspondence between the season and the act. As He has just said, 'He had been daily with them in the Temple,' but in the blaze of the noontide they laid no hands upon Him. They found a congenial hour in the midnight. But the words go a great deal deeper than allusive …
Alexander Maclaren—Expositions Of Holy Scripture

The Duty of Constant Communion J. W.
"Do this in remembrance of me." Luke 22:19. It is no wonder that men who have no fear of God should never think of doing this. But it is strange that it should be neglected by any that do fear God, and desire to save their souls; And yet nothing is more common. One reason why many neglect it is, they are so much afraid of "eating and drinking unworthily," that they never think how much greater the danger is when they do not eat or drink it at all. That I may do what I can to bring these well-meaning …
John Wesley—Sermons on Several Occasions

Gethsemane
"And all the unknown joys he gives, Were bought with agonies unknown." Since it would not be possible for any believer, however experienced, to know for himself all that our Lord endured in the place of the olivepress, when he was crushed beneath the upper and the nether mill-stone of mental suffering and hellish malice, it is clearly far beyond the preacher's capacity to set it forth to you. Jesus himself must give you access to the wonders of Gethsemane: as for me, I can but invite you to enter …
Charles Haddon Spurgeon—Spurgeon's Sermons Volume 9: 1863