And the LORD said furthermore to him, Put now your hand into your bosom. And he put his hand into his bosom: and when he took it out…
1. Some give it a moral signification — as that the leprous hand of Moses showeth the works of the law that justifieth not.
2. Some give it a mystical signification — that the leprous hand of the synagogue of the Jews was cast off as the leprous person out of the house, and the hand restored betokeneth the Gentile Church adopted instead of the Jewish.
3. Some refer it to Christ, that He being the Hand, that is, the power of His Father, by taking our nature upon Him, became as it were leprous, that is, deformed, by His sufferings and passion, but by His resurrection and ascension His glory appeareth.
4. Some give it an historical signification — by the leprous hand they understand the miserable state of the Hebrews in the time of their cruel servitude, who in their deliverance received their former liberty.
5. Some think that the leprous hand signifieth the pollutions of Egypt, wherewith Israel was defiled, who being delivered were restored to the true worship of God.
6. That the first sending of Moses to the Israelites brought upon them more cruel treatment, but his after ministry brought them joy and deliverance.
7. That the hand being the instrument of working, betokeneth the ministry and authority of Moses, and that God would use a weak instrument to effect His will, Moses having lived a long time in banishment seemed a thing leprous and vile, yet God should in this His service make him a glorious vessel and instrument.
8. That as the leprosy is only cured by God, so their deliverance was only God's work, and to humble Moses by the remembrance of his own infirmity.
9. As far as the intrinsic significancy of the sign is concerned, it was evidently calculated to teach that whatever is new, vigorous, vital, and flourishing, may at once be withered at the word of Omnipotence; and again with equal facility restored to its pristine condition.
(J. S. Exell, M. A.)
Parallel VersesKJV: And the LORD said furthermore unto him, Put now thine hand into thy bosom. And he put his hand into his bosom: and when he took it out, behold, his hand was leprous as snow.