4:25 This is the first mention of Adam in the story of this chapter . No question the murder of Abel, and the impenitency and apostacy of Cain, were a very great grief to him and Eve, and the more because their own wickedness did now correct them, and their backsliding did reprove them. Their folly had given sin and death entrance into the world, and now they smarted by it, being by means thereof deprived of both their sons in one day, Gen 27:45. When parents are grieved by their children's wickedness, they should take occasion from thence to lament that corruption of nature which was derived from them, and which is the root of bitterness. But here we have that which was a relief to our first parents in their affliction, namely, God gave them to see the rebuilding of their family which was sorely shaken and weakened by that sad event. For, they saw their seed, another instead of Abel. And Adam called his name Seth - That is, Set, settled or placed, because in his seed mankind should continue to the end of time.

Genesis 4:25 Parallel Commentaries

How the Kindly-Disposed and the Envious are to be Admonished.
(Admonition 11.) Differently to be admonished are the kindly-disposed and the envious. For the kindly-disposed are to be admonished so to rejoice in what is good in others as to desire to have the like as their own; so to praise with affection the deeds of their neighbours as also to multiply them by imitation, lest in this stadium of the present life they assist at the contest of others as eager backers, but inert spectators, and remain without a prize after the contest, in that they toiled not …
Leo the Great—Writings of Leo the Great

Epistle cxxii. To Rechared, King of the visigoths .
To Rechared, King of the Visigoths [82] . Gregory to Rechared, &c. I cannot express in words, most excellent son, how much I am delighted with thy work and thy life. For on hearing of the power of a new miracle in our days, to wit that the whole nation of the Goths has through thy Excellency been brought over from the error of Arian heresy to the firmness of a right faith, one is disposed to exclaim with the prophet, This is the change wrought by the right hand of the Most High (Ps. lxxvi. 11 [83] …
Saint Gregory the Great—the Epistles of Saint Gregory the Great

The Growth of the Old Testament Prophetic Histories
[Sidenote: Analogies between the influences that produced the two Testaments] Very similar influences were at work in producing and shaping both the Old and the New Testaments; only in the history of the older Scriptures still other forces can be distinguished. Moreover, the Old Testament contains a much greater variety of literature. It is also significant that, while some of the New Testament books began to be canonized less than a century after they were written, there is clear evidence that …
Charles Foster Kent—The Origin & Permanent Value of the Old Testament