Mark 3:21
Parallel Verses
New American Standard Bible
When His own people heard of this, they went out to take custody of Him; for they were saying, "He has lost His senses."

King James Bible
And when his friends heard of it, they went out to lay hold on him: for they said, He is beside himself.

Darby Bible Translation
And his relatives having heard of it went out to lay hold on him, for they said, He is out of his mind.

World English Bible
When his friends heard it, they went out to seize him: for they said, "He is insane."

Young's Literal Translation
and his friends having heard, went forth to lay hold on him, for they said that he was beside himself,

Mark 3:21 Parallel
Barnes' Notes on the Bible

When his friends - Greek, "they who were of him." Not the apostles, but his relatives, his friends, who were in the place of his nativity.

Heard of it - Heard of his conduct: his preaching; his appointing the apostles; his drawing such a multitude to his preaching. This shows that by "his friends" were not meant the apostles, but his neighbors and others who "heard" of his conduct.

They went out to lay hold on him - To take him away from the multitude, and to remove him to his home, that he might be treated as a maniac, so that, by absence from the "causes" of excitement, he might be restored to his right mind.

They said - That is, common report said; or his friends and relatives said, for they did not believe on him, John 7:5. Probably the enemies of Jesus raised the report, and his relatives were persuaded to believe it to be true.

He is beside himself - He is delirious or deranged. The reason why this report gained any belief was, probably, that he had lived among them as a carpenter; that he was poor and unknown; and that now, at 30 years of age, he broke off from his occupations, abandoned his common employment, spent much time in the deserts, denied himself the common comforts of life, and set up his claims to be the Messiah who was expected by all the people to come with great pomp and splendor. The charge of "derangement" on account of attention to religion has not been confined to the Saviour. Let a man be made deeply sensible of his sins, and spend much of his time in prayer, and have no relish for the ordinary amusements or business of life; or let a Christian be much impressed with his obligation to devote himself to God, and "act" as if he believed there was an "eternity," and warn his neighbors of their danger; or let a minister show uncommon zeal and spend his strength in the service of his Master, and the world is not slow to call it derangement. And none will be more ready to originate or believe the charge than an ungodly and infidel parent or brother, a self-righteous Pharisee or professor in the church. At the same time, men may endanger themselves on the bosom of the deep or in the bowels of the earth for wealth; or may plunge into the vortex of fashion, folly, and vice, and break in upon the hours of repose, and neglect their duties to their family and the demands of business, and in the view of the world it is wisdom and proof of a sane mind! Such is the consistency of boasted reason; such the wisdom and prudence of worldly men!

Mark 3:21 Parallel Commentaries

Christ's Relations
'Whosoever shall do the will of God, the same is My brother, and My sister, and mother.'--Mark iii. 35. There was a conspiracy to seize Jesus because He is 'mad,' and Mary was in the plot! I. The example for us. (1) Of how all natural and human ties and affections are to be subordinated to doing God's will. Obedience to Him is the first and main thing to which everything else bows, and which determines everything. If others compete or interfere, reject them. Out of that common obedience new ties
Alexander Maclaren—Expositions of Holy Scripture

Christ's Kindred
'There came then His brethren and His mother, and, standing without, sent unto Him, calling Him. 32. And the multitude sat about Him; and they said unto Him, Behold, Thy mother and Thy brethren without seek for Thee. 33. And He answered them, saying, Who is My mother, or My brethren? 34. And He looked round about on them which sat about Him, and said, Behold My mother and My brethren! 35. For whosoever shall do the will of God, the same is My brother, and My sister, and mother.'--Mark iii. 31-35.
Alexander Maclaren—Expositions of Holy Scripture

Life and Character of John
"Volat avis sine meta, Quo nec votes nec propheta Evolavit altius: Tam implenda quam impleta, Numquam vidit tot secreta Purus homo purius. (Adam of St. Victor.) The Mission of John. Peter, the Jewish apostle of authority, and Paul, the Gentile apostle of freedom, had done their work on earth before the destruction of Jerusalem--had done it for their age and for all ages to come; had done it, and by the influence of their writings are doing it still, in a manner that can never be superseded. Both
Philip Schaff—History of the Christian Church, Volume I

Whether the Sin against the Holy Ghost is the Same as the Sin Committed through Certain Malice?
Objection 1: It would seem that the sin against the Holy Ghost is not the same as the sin committed through certain malice. Because the sin against the Holy Ghost is the sin of blasphemy, according to Mat. 12:32. But not every sin committed through certain malice is a sin of blasphemy: since many other kinds of sin may be committed through certain malice. Therefore the sin against the Holy Ghost is not the same as the sin committed through certain malice. Objection 2: Further, the sin committed through
Saint Thomas Aquinas—Summa Theologica

Cross References
2 Kings 9:11
Now Jehu came out to the servants of his master, and one said to him, "Is all well? Why did this mad fellow come to you?" And he said to them, "You know very well the man and his talk."

Jeremiah 29:26
"The LORD has made you priest instead of Jehoiada the priest, to be the overseer in the house of the LORD over every madman who prophesies, to put him in the stocks and in the iron collar,

Mark 3:31
Then His mother and His brothers arrived, and standing outside they sent word to Him and called Him.

John 7:3
Therefore His brothers said to Him, "Leave here and go into Judea, so that Your disciples also may see Your works which You are doing.

John 7:5
For not even His brothers were believing in Him.

John 7:10
But when His brothers had gone up to the feast, then He Himself also went up, not publicly, but as if, in secret.

John 10:20
Many of them were saying, "He has a demon and is insane. Why do you listen to Him?"

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