Verse 24-28. This discourse is also recorded in Mr 8:34-38; 9:1 and Lu 9:23-27

Let him deny himself. That is, let him surrender to God his will, affections, body, and soul. Let him not seek his own happiness as the supreme object, but be willing to renounce all, and lay down his life also, if required.

Take up his cross. See Barnes "Mt 10:38".

{x} "any man" Mt 10:38; Mr 8:34; Lu 9:23; 14:27; Ac 14:22; 1 Th 3:3